Pages
Products

COMT


Official Full Name
catechol-O-methyltransferase
Organism
Homo sapiens
Gene ID
1312
Background
Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
Synonyms
HEL-S-98n

Cat.No. Product Name Price
SHH267697 shRNA set against Rat COMT (NM_012531.2) Inquiry
SHG192095 shRNA set against Rat Comt(NM_012531.2) Inquiry
SHG192131 shRNA set against Mouse Comt(NM_007744.3) Inquiry
SHH267689 shRNA set against Human COMT (NM_000754.3) Inquiry
SHH267693 shRNA set against Mouse COMT (NM_007744.3) Inquiry
Cat.No. Product Name Price
CDCB160291 Human COMT ORF clone (NM_000754) Inquiry
MiUTR1R-01120 COMT miRNA 3'UTR clone Inquiry
MiUTR1M-03226 COMT miRNA 3'UTR clone Inquiry
MiUTR1H-02348 COMT miRNA 3'UTR clone Inquiry
MiUTR1H-02347 COMT miRNA 3'UTR clone Inquiry
MiUTR1H-02346 COMT miRNA 3'UTR clone Inquiry
CDFR010352 Rat Comt cDNA Clone(NM_012531.2) Inquiry
CDFH004071 Human COMT cDNA Clone(NM_001135162.1) Inquiry
MiUTR3H-00365 COMT miRNA 3'UTR clone Inquiry
CDFH004070 Human COMT cDNA Clone(NM_001135161.1) Inquiry
SKO0401 COMT Validated sgRNA vector Inquiry
CDCS405880 Human COMT ORF Clone (BC011935) Inquiry
CDCR377279 Rat Comt ORF Clone(NM_012531.2) Inquiry
CDCR350257 Human COMT ORF Clone(NM_001135162.1) Inquiry
CDCR350255 Human COMT ORF Clone(NM_001135161.1) Inquiry
CDCR236685 Mouse Comt ORF Clone(NM_001111063.1) Inquiry
CDCR236683 Mouse Comt ORF Clone(NM_001111062.1) Inquiry
CDCR049564 Human COMT ORF clone (NM_000754.3) Inquiry
CDCS405881 Human COMT ORF Clone (BC000419) Inquiry
Quick Inquiry