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shRNA set against Rat ACVR1B (NM_199230.1)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH231234

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Gene Information

Cat. No. SHH231234
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ACVR1B
Gene Name Acvr1b activin A receptor, type 1B [ Mus musculus ]
Species Rat
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Acvr1b activin A receptor, type 1B [ Mus musculus ]
Gene Symbol Acvr1b
Synonyms Alk4; SKR2; ActRIB; ActR-IB; Acvrlk4; 6820432J04
Gene Description activin A receptor, type 1B
GeneID 11479
Uni ProtID Q3TZF1
mRNA Refseq NM_007395.3
Protein Refseq NP_031421.1
Chromosome Location 15 F2; 15 60.4 cM
Function ATP binding; SMAD binding; activin binding; activin receptor activity, type I; inhibin binding; kinase activity; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; ubiquitin protein ligase binding;
Pathway Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; PluriNetWork, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem;
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