Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CLOE-2261 Host Cell : HEK293
| Cat. No. | CLOE-2261 |
| Introduction | This cell lysate over-expresses mouse Acvr1b (NP_031421.1) (Met1-Glu126) fused with human IgG1-Fc at the C-terminus. Purification of target protein (s) from this cell lysate has been verified. |
| Target Gene | Acvr1b |
| Host Cell | HEK293 |
| Host Cell Species | Homo sapiens (Human) |
| Applications | Positive control for Western Blot (WB), antibody verification, protein purification |
| Growth Properties | Cells are cultured as a monolayer at 37°C in a humidified atmosphere with 5% CO2. Split at 80-90% confluence, approximately 1:3-1:6. |
| Media Type | Cells were cultured in DMEM supplemented with 10% fetal bovine serum. |
| Freeze Medium | Complete medium supplemented with 10% (v/v) DMSO |
| Storage | Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided. |
| Shipping | Ice package |
| Gene Name | Acvr1b activin A receptor, type 1B [ Mus musculus ] |
| Gene Symbol | Acvr1b |
| Synonyms | Alk4; SKR2; ActRIB; ActR-IB; Acvrlk4; 6820432J04 |
| Gene Description | activin A receptor, type 1B |
| GeneID | 11479 |
| Uni ProtID | Q3TZF1 |
| mRNA Refseq | NM_007395.3 |
| Protein Refseq | NP_031421.1 |
| Chromosome Location | 15 F2; 15 60.4 cM |
| Function | ATP binding; SMAD binding; activin binding; activin receptor activity, type I; inhibin binding; kinase activity; metal ion binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups; transforming growth factor beta-activated receptor activity; transmembrane receptor protein serine/threonine kinase activity; ubiquitin protein ligase binding; |
| Pathway | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Developmental Biology, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; PluriNetWork, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; |
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