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shRNA set against Mouse RAPGEF3 (NM_144850.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH389680

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Gene Information

Cat. No. SHH389680
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr RAPGEF3
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Target Gene RAPGEF3
Background Enables guanyl-nucleotide exchange factor activity and protein domain specific binding activity. Involved in several processes, including Rap protein signal transduction; cellular response to cAMP; and regulation of syncytium formation by plasma membrane fusion. Located in several cellular components, including filopodium; lamellipodium; and microvillus. Implicated in nicotine dependence. Biomarker of congestive heart failure. [provided by Alliance of Genome Resources, Feb 2025]
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