Panoply™ Human RAPGEF3 Knockdown Stable Cell Line

Name: Panoply™ Human RAPGEF3 Knockdown Stable Cell Line
SKU: CSC-DC012969
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC012969

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC012969
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	RAPGEF3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 [ Homo sapiens ]
Gene Symbol	RAPGEF3
Synonyms	RAPGEF3; Rap guanine nucleotide exchange factor (GEF) 3; RAP guanine nucleotide exchange factor (GEF) 3; rap guanine nucleotide exchange factor 3; bcm910; cAMP GEFI; EPAC; exchange protein directly activated by cAMP 1; EPAC 1; 9330170P05Rik; exchange factor directly activated by cAMP 1; cAMP-regulated guanine nucleotide exchange factor I; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP; EPAC1; HSU79275; CAMP-GEFI; MGC21410;
Gene ID	10411
Uni Prot ID	O95398
m RNA Refseq	BC040534
Chromosome Location	12q13.1
Function	cAMP binding; cAMP-dependent
Pathway	Adaptive Immune System, organism-specific biosystem; Hemostasis, organism-specific biosystem; Immune System, organism-specific biosystem; Integration of energy metabolism, organism-specific biosystem; Integrin alphaIIb beta3 signaling, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Leukocyte transendothelial migration, organism-specific biosystem;
MIM	606057

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