shRNA set against Mouse Psen1(NM_008943.2)

Name: shRNA set against Mouse Psen1(NM_008943.2)
SKU: SHR145878
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHR145878

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Gene Information

Cat. No.	SHR145878
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	Psen1
Gene Name	Psen1 presenilin 1 [ Mus musculus ]
Species	Mouse
Report Gene	eGFP
Content	Each set contains 4 shRNA expression constructs.
Promoter	H1
Selection Marker	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg

Gene Name	Psen1 presenilin 1 [ Mus musculus ]
Gene Symbol	Psen1
Synonyms	PS1; Ad3h; PS-1; S182
Gene Description	presenilin 1
GeneID	19164
Uni ProtID	P49769
mRNA Refseq	NM_008943.2
Protein Refseq	NP_032969.1
Chromosome Location	12 D1; 12 37.0 cM
Function	PDZ domain binding; aspartic-type endopeptidase activity; beta-catenin binding; cadherin binding; calcium channel activity; endopeptidase activity; endopeptidase activity; endopeptidase activity; hydrolase activity; peptidase activity; protein binding;
Pathway	Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem;

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