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shRNA set against Mouse ERCC1 (NM_007948.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH286881

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Gene Information

Cat. No. SHH286881
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ERCC1
Gene Name Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Ercc1 excision repair cross-complementing rodent repair deficiency, complementation group 1 [ Mus musculus ]
Gene Symbol Ercc1
Synonyms Ercc-1
Gene Description excision repair cross-complementing rodent repair deficiency, complementation group 1
GeneID 13870
Uni ProtID E9PUM0
mRNA Refseq NM_001127324.1
Protein Refseq NP_001120796.1
Chromosome Location 7 A3; 7 4.0 cM
Function DNA binding; damaged DNA binding; endonuclease activity; hydrolase activity; nuclease activity; protein C-terminus binding; protein domain specific binding; single-stranded DNA binding;
Pathway DNA Repair, organism-specific biosystem; Dual incision reaction in GG-NER, organism-specific biosystem; Dual incision reaction in TC-NER, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Formation of incision complex in GG-NER, organism-specific biosystem; Formation of transcription-coupled NER (TC-NER) repair complex, organism-specific biosystem;
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