shRNA set against Mouse CHUK (NM_007700.2)

Name: shRNA set against Mouse CHUK (NM_007700.2)
SKU: SHH263933
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH263933

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Product Information

Gene Information

Cat. No.	SHH263933
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	CHUK
Gene Name	Chuk conserved helix-loop-helix ubiquitous kinase [ Mus musculus ]
Species	Mouse
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	Chuk conserved helix-loop-helix ubiquitous kinase [ Mus musculus ]
Gene Symbol	Chuk
Synonyms	IKK1; Ikka; Chuk1; Fbx24; IKBKA; Fbxo24; NFKBIKA; AI256658
Gene Description	conserved helix-loop-helix ubiquitous kinase
GeneID	12675
Uni ProtID	E9Q605
mRNA Refseq	NM_001162410.1
Protein Refseq	NP_001155882.1
Chromosome Location	19 C3; 19 45.0 cM
Function	ATP binding; contributes_to IkappaB kinase activity; kinase activity; nucleotide binding; protein binding; protein heterodimerization activity; protein kinase activity; protein kinase activity; protein serine/threonine kinase activity; receptor signaling protein serine/threonine kinase activity; transferase activity; transferase activity, transferring phosphorus-containing groups;
Pathway	AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem;

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