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Panoply™ Human CHUK Knockdown Stable Cell Line

Cat.No.
CSC-DC003164
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CHUK
Synonyms
IKK1; IKKA; IKBKA; TCF16; NFKBIKA; IKK-alpha
Gene Description
conserved helix-loop-helix ubiquitous kinase
Gene ID
UniProt ID
O15111
mRNA Refseq
Protein Refseq
Chromosome Location
10q24-q25
Function
ATP binding; IkappaB kinase activity; protein binding; protein kinase activity;
Pathway
AKT phosphorylates targets in the cytosol, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem;
MIM

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