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shRNA set against Mouse APOE (NM_009696.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH238546

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Gene Information

Cat. No. SHH238546
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr APOE
Gene Name Apoe apolipoprotein E [ Mus musculus ]
Species Mouse
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name Apoe apolipoprotein E [ Mus musculus ]
Gene Symbol Apoe
Synonyms AI255918
Gene Description apolipoprotein E
GeneID 11816
Uni ProtID P08226
mRNA Refseq NM_009696.3
Protein Refseq NP_033826.2
Chromosome Location 7 A3; 7 4.0 cM
Function antioxidant activity; beta-amyloid binding; cholesterol transporter activity; heparin binding; hydroxyapatite binding; identical protein binding; lipid binding; lipid transporter activity; lipoprotein particle binding; low-density lipoprotein particle receptor binding; metal chelating activity; phosphatidylcholine-sterol O-acyltransferase activator activity; phosphatidylcholine-sterol O-acyltransferase activator activity; phospholipid binding; protein heterodimerization activity; protein homodimerization activity; tau protein binding; very-low-density lipoprotein particle receptor binding;
Pathway Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Chylomicron-mediated lipid transport, organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Lipid digestion, mobilization, and transport, organism-specific biosystem; Lipoprotein metabolism, organism-specific biosystem; Metabolism, organism-specific biosystem;
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