shRNA set against Human XRN1 (NM_019001.3)

Name: shRNA set against Human XRN1 (NM_019001.3)
SKU: SHH448156
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH448156

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Gene Information

Cat. No.	SHH448156
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	XRN1
Gene Name	XRN1 5-3 exoribonuclease 1 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	XRN1 5-3 exoribonuclease 1 [ Homo sapiens ]
Gene Symbol	XRN1
Synonyms	SEP1
Gene Description	5-3 exoribonuclease 1
GeneID	54464
Uni ProtID	Q8IZH2
mRNA Refseq	NM_001042604.1
Protein Refseq	NP_001036069.1
Chromosome Location	3q23
Function	5-3 exonuclease activity; DNA binding; RNA binding; protein binding;
Pathway	Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; Regulation of mRNA Stability by Proteins that Bind AU-rich Elements, organism-specific biosystem;
MIM	607994

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