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XRN1


Official Full Name
5'-3' exoribonuclease 1
Organism
Homo sapiens
Gene ID
54464
Background
This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Synonyms
45901

Cat.No. Product Name Price
SHH448156 shRNA set against Human XRN1 (NM_019001.3) Inquiry
SHH448160 shRNA set against Mouse XRN1 (NM_011916.2) Inquiry
SHL138982 shRNA set against Human XRN1(NM_001042604.1) Inquiry
SHL139165 shRNA set against Mouse Xrn1(NM_011916.2) Inquiry
SHL139194 shRNA set against Human XRN1(NM_019001.3) Inquiry
SHL139212 shRNA set against Human XRN1(NM_001042604.1) Inquiry
SHW017151 shRNA set against Danio rerio XRN1 (NM_201033) Inquiry
Cat.No. Product Name Price
CDCH101908 Mouse Xrn1 ORF clone (NM_011916.2) Inquiry
CDFH021385 Human XRN1 cDNA Clone(NM_001042604.1) Inquiry
CDFL015212 Mouse Xrn1 cDNA Clone(NM_011916.2) Inquiry
MiUTR1H-11324 XRN1 miRNA 3'UTR clone Inquiry
MiUTR1H-11325 XRN1 miRNA 3'UTR clone Inquiry
MiUTR1M-12861 XRN1 miRNA 3'UTR clone Inquiry
CDCB178626 Danio rerio XRN1 ORF Clone (NM_201033) Inquiry
CDCB186919 Rabbit XRN1 ORF clone (XM_002716566.2) Inquiry
CDCH101904 human XRN1 ORF clone (NM_001042604.1) Inquiry
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