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shRNA set against Human TNK2 (NM_005781.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH432272

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Gene Information

Cat. No. SHH432272
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr TNK2
Gene Name TNK2 tyrosine kinase, non-receptor, 2 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name TNK2 tyrosine kinase, non-receptor, 2 [ Homo sapiens ]
Gene Symbol TNK2
Synonyms ACK; ACK1; ACK-1; p21cdc42Hs
Gene Description tyrosine kinase, non-receptor, 2
GeneID 10188
Uni ProtID Q07912
mRNA Refseq NM_001010938.1
Protein Refseq NP_001010938.1
Chromosome Location 3q29
Function ATP binding; GTPase inhibitor activity; WW domain binding; epidermal growth factor receptor binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity;
Pathway CDC42 signaling events, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem;
MIM 606994
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