Human TNK2 adenoviral particles

Name: Human TNK2 adenoviral particles
SKU: AD16698Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD16698Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD16698Z
Description	Adenovirus with ORF of tyrosine kinase, non-receptor, 2 (TNK2), transcript variant 2.
Gene	TNK2
Species	Human
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	TNK2 tyrosine kinase, non-receptor, 2 [ Homo sapiens ]
Gene Symbol	TNK2
Synonyms	ACK; ACK1; ACK-1; p21cdc42Hs
Gene Description	tyrosine kinase, non-receptor, 2
GeneID	10188
Uni ProtID	Q07912
mRNA Refseq	NM_001010938.1
Protein Refseq	NP_001010938.1
Chromosome Location	3q29
Function	ATP binding; GTPase inhibitor activity; WW domain binding; epidermal growth factor receptor binding; metal ion binding; non-membrane spanning protein tyrosine kinase activity; protein binding; protein serine/threonine kinase activity; protein serine/threonine/tyrosine kinase activity; protein tyrosine kinase activity;
Pathway	CDC42 signaling events, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Focal Adhesion, organism-specific biosystem; G13 Signaling Pathway, organism-specific biosystem;
MIM	606994

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