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shRNA set against Human SOD1 (NM_000454.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH415020

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Gene Information

Cat. No. SHH415020
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr SOD1
Gene Name SOD1 superoxide dismutase 1, soluble [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name SOD1 superoxide dismutase 1, soluble [ Homo sapiens ]
Gene Symbol SOD1
Synonyms ALS; SOD; ALS1; IPOA; hSod1; homodimer
Gene Description superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult))
GeneID 6647
Uni ProtID P00441
mRNA Refseq NM_000454.4
Protein Refseq NP_000445.1
Chromosome Location 21q22.11
Function chaperone binding; copper ion binding; protein binding; protein homodimerization activity; protein phosphatase 2B binding; superoxide dismutase activity; zinc ion binding;
Pathway Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Hemostasis, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem;
MIM 147450
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