Recombinant Human SOD1 (N-6His)

Name: Recombinant Human SOD1 (N-6His)
SKU: RP00285
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00285 Tag : N-6His

Expressed Region : Met1-Gln154 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00285
Description	The Recombinant Human SOD1 (N-6His) is produced in our E.coli expression system. The amino acid region expressed is Met1-Gln154 with a 6His tag at the N terminus.
Species	Human
Tag	N-6His
Mol Weight	18.1 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Met1-Gln154
Expression System	E.coli
Formulation	Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	SOD1
Synonyms	Superoxide Dismutase [Cu-Zn]; Superoxide Dismutase 1; hSod1; SOD1

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The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. In addition, this protein contains an antimicrobial peptide that displays antibacterial, antifungal, and anti-MRSA activity against E. coli, E. faecalis, S. aureus, S. aureus MRSA LPV+, S. agalactiae, and yeast C. krusei. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.

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