shRNA set against Human RAD50 (NM_005732.3)

Name: shRNA set against Human RAD50 (NM_005732.3)
SKU: SHH388984
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH388984

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Product Information

Gene Information

Cat. No.	SHH388984
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	RAD50
Gene Name	RAD50 RAD50 homolog (S. cerevisiae) [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	RAD50 RAD50 homolog (S. cerevisiae) [ Homo sapiens ]
Gene Symbol	RAD50
Synonyms	NBSLD; RAD502; hRad50
Gene ID	10111
Uni Prot ID	A5D6Y3
m RNA Refseq	NM_005732.3
Protein Refseq	NP_005723.2
Chromosome Location	5q31
Function	contributes_to 3-5 exonuclease activity; ATP binding; contributes_to ATP-dependent DNA helicase activity; DNA binding; protein binding; protein binding, bridging; contributes_to single-stranded DNA specific endodeoxyribonuclease activity; zinc ion binding;
Pathway	Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA damage response, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem;
MIM	604040

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