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Panoply™ Human RAD50 Knockdown Stable Cell Line

Cat.No.
CSC-DC012910
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
RAD50
Synonyms
NBSLD; RAD502; hRad50
Gene ID
UniProt ID
A5D6Y3
mRNA Refseq
Protein Refseq
Chromosome Location
5q31
Function
contributes_to 3-5 exonuclease activity; ATP binding; contributes_to ATP-dependent DNA helicase activity; DNA binding; protein binding; protein binding, bridging; contributes_to single-stranded DNA specific endodeoxyribonuclease activity; zinc ion binding;
Pathway
Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; DNA Repair, organism-specific biosystem; DNA damage response, organism-specific biosystem; Double-Strand Break Repair, organism-specific biosystem; Homologous Recombination Repair, organism-specific biosystem;
MIM

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