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Human Rad50 Knockdown Cell Line-HeLa

Human Rad50 Knockdown Cell Line-HeLa

Cat.No. :  CSC-RK0012

Host Cell:  HeLa Validation:  Real-Time RCR

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Cell Line Information

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Cat. No. CSC-RK0012
Background This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. A similar protein has been disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
Gene RAD50
Alias RAD50, hRad50, RAD50 2, NBSLD, RAD502
Host Cell HeLa
Host Cell Species Homo sapiens (Human)
Morphology Epithelial
Stability Validated for at least 10 passages
Application

(1) Studying gene functions

(2) Studying gene interactions and signaling pathways

(3) Target validation and drug discovery

(4) Designing diseases models

Size Form >1 × 10^6 cells / vial
Shipping Dry ice
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations

The following safety precautions should be observed.

1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.

2. No eating, drinking or smoking while handling the stable line.

3. Wash hands after handling the stable line and before leaving the lab.

4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.

5. All waste should be considered hazardous.

6. Dispose of all liquid waste after each experiment and treat with bleach.

Ship Dry ice
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