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shRNA set against Human PTPN11 (NM_002834.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH386432

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Gene Information

Cat. No. SHH386432
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr PTPN11
Gene Name PTPN11 protein tyrosine phosphatase, non-receptor type 11 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name PTPN11 protein tyrosine phosphatase, non-receptor type 11 [ Homo sapiens ]
Gene Symbol PTPN11
Synonyms CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3
Gene Description protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1)
Gene ID 5781
Uni Prot ID Q06124
m RNA Refseq NM_002834.3
Protein Refseq NP_002825.3
Chromosome Location 12q24
Pathway Adaptive Immune System, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CTLA4 inhibitory signaling, organism-specific biosystem;
MIM 176876
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