shRNA set against Human PML(NM_033244.3)

Name: shRNA set against Human PML(NM_033244.3)
SKU: SHR123961
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHR123961

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Product Information

Gene Information

Cat. No.	SHR123961
Description	Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr	PML
Gene Name	PML promyelocytic leukemia [ Homo sapiens ]
Species	Human
Content	Each set contains 4 shRNA expression constructs.
Promoter	U6
Selection Marker	Puromycin
Format	5 μg purified plasmid
Unit Size	5 μg

Gene Name	PML promyelocytic leukemia [ Homo sapiens ]
Gene Symbol	PML
Synonyms	MYL; RNF71; PP8675; TRIM19
Gene Description	promyelocytic leukemia
GeneID	5371
Uni ProtID	P29590
mRNA Refseq	NM_002675.3
Protein Refseq	NP_002666.1
Chromosome Location	15q22
Function	DNA binding; SMAD binding; SUMO binding; cobalt ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription coactivator activity; ubiquitin protein ligase binding; zinc ion binding; zinc ion binding;
Pathway	Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; DNA damage response, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem;
MIM	102578

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