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shRNA set against Human NCOA1 (NM_003743.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH350072

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Gene Information

Cat. No. SHH350072
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr NCOA1
Gene Name NCOA1 nuclear receptor coactivator 1 [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name NCOA1 nuclear receptor coactivator 1 [ Homo sapiens ]
Gene Symbol NCOA1
Synonyms SRC1; KAT13A; RIP160; F-SRC-1; bHLHe42; bHLHe74
Gene Description nuclear receptor coactivator 1
GeneID 8648
Uni ProtID Q15788
mRNA Refseq NM_147223.2
Protein Refseq NP_671756.1
Chromosome Location 2p23
Function DNA binding; androgen receptor binding; chromatin binding; enzyme binding; histone acetyltransferase activity; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; protein N-terminus binding; protein binding; protein dimerization activity; signal transducer activity; transcription coactivator activity; transcription coactivator activity;
Pathway Activation of Gene Expression by SREBP (SREBF), organism-specific biosystem; Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Circadian Repression of Expression by REV-ERBA, organism-specific biosystem; Developmental Biology, organism-specific biosystem;
MIM 602691
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