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NCOA1

Official Full Name
nuclear receptor coactivator 1
Organism
Homo sapiens
GeneID
8648
Background
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Synonyms
SRC1; KAT13A; RIP160; F-SRC-1; bHLHe42; bHLHe74;

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