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shRNA set against Human MECOM (NM_005241.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH339787

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Gene Information

Cat. No. SHH339787
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr MECOM
Gene Name MECOM MDS1 and EVI1 complex locus [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name MECOM MDS1 and EVI1 complex locus [ Homo sapiens ]
Gene Symbol MECOM
Synonyms EVI1; MDS1; PRDM3; MDS1-EVI1; AML1-EVI-1
Gene ID 2122
Uni Prot ID Q03112
m RNA Refseq BC069498
Chromosome Location 3q26
Function DNA binding; protein binding; protein homodimerization activity; NOT protein homodimerization activity; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; zinc ion binding;
Pathway Chronic myeloid leukemia, organism-specific biosystem; Chronic myeloid leukemia, conserved biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, conserved biosystem; Pathways in cancer, organism-specific biosystem;
MIM 165215
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