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Rat Mecom cDNA Clone(NM_001106423.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006160

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Gene Information

Cat. No. CDFR006160
Description NativeORF clone of Rattus norvegicus ecotropic viral integration site 1 (Evi1) as transfection-ready DNA NM_001106423.1
Product Type cDAN Clone
Gene Abbr Mecom
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene MECOM
Background The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
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