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shRNA set against Human MC4R (NM_005912.2)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH339063

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Gene Information

Cat. No. SHH339063
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr MC4R
Gene Name MC4R melanocortin 4 receptor [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name MC4R melanocortin 4 receptor [ Homo sapiens ]
Gene Symbol MC4R
Gene Description melanocortin 4 receptor
Gene ID 4160
Uni Prot ID P32245
m RNA Refseq NM_005912.2
Protein Refseq NP_005903.2
Chromosome Location 18q22
Function melanocortin receptor activity; melanocyte-stimulating hormone receptor activity; neuropeptide binding; peptide hormone binding; protein binding; ubiquitin protein ligase binding;
Pathway Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem;
MIM 155541
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