shRNA set against Human MAPK8 (NM_002750.2)

Name: shRNA set against Human MAPK8 (NM_002750.2)
SKU: SHH338075
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH338075

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Product Information

Gene Information

Cat. No.	SHH338075
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	MAPK8
Gene Name	MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Gene Symbol	MAPK8
Synonyms	JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2
Gene Description	mitogen-activated protein kinase 8
Gene ID	5599
Uni Prot ID	A1L4K2
m RNA Refseq	NM_139047.1
Protein Refseq	NP_620635.1
Chromosome Location	10q11.22
Function	ATP binding; JUN kinase activity; histone deacetylase binding; histone deacetylase regulator activity; protein binding; protein serine/threonine kinase activity;
Pathway	ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation of BIM and translocation to mitochondria, organism-specific biosystem; Activation of BMF and translocation to mitochondria, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem;
MIM	601158

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