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MAPK8


Official Full Name
mitogen-activated protein kinase 8
Organism
Homo sapiens
Gene ID
5599
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
Synonyms
JNK; JNK1; PRKM8; SAPK1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2

Cat.No. Product Name Price
SHH175943 shRNA set against Human MAPK8(NM_139046.1) Inquiry
SHH338075 shRNA set against Human MAPK8 (NM_002750.2) Inquiry
SHH175907 shRNA set against Human MAPK8(NM_139047.1) Inquiry
SHH175961 shRNA set against Human MAPK8(NM_002750.2) Inquiry
SHH175979 shRNA set against Human MAPK8(NM_139049.1) Inquiry
SHH338079 shRNA set against Mouse MAPK8 (NM_016700.4) Inquiry
Cat.No. Product Name Price
CDFG008370 Human MAPK8 cDNA Clone(NM_139046.1) Inquiry
MiUTR1H-06088 MAPK8 miRNA 3'UTR clone Inquiry
MiUTR1H-06087 MAPK8 miRNA 3'UTR clone Inquiry
CDFH011046 Human MAPK8 cDNA Clone(NM_002750.2) Inquiry
CDFG008376 Human MAPK8 cDNA Clone(NM_139049.1) Inquiry
CDFG008374 Human MAPK8 cDNA Clone(NM_139049.1) Inquiry
CDFG008372 Human MAPK8 cDNA Clone(NM_139047.1) Inquiry
CDFG008371 Human MAPK8 cDNA Clone(NM_139047.1) Inquiry
MiUTR1H-06090 MAPK8 miRNA 3'UTR clone Inquiry
CDCL185271 Human MAPK8 ORF clone(NM_139047.1) Inquiry
MiUTR1H-06089 MAPK8 miRNA 3'UTR clone Inquiry
CDCS410938 Human MAPK8 ORF Clone (BC130570) Inquiry
CDCR317166 Human MAPK8 ORF Clone(NM_139046.1) Inquiry
CDCR252924 Mouse Mapk8 ORF Clone(NM_016700.4) Inquiry
CDCL130499 Human MAPK8 ORF clone (NM_139049.1) Inquiry
CDCL130495 Mouse MAPK8 ORF clone (NM_002750.2) Inquiry
CDCB189657 Rabbit MAPK8 ORF clone (XM_002722670.2) Inquiry
CDCB157343 Mouse MAPK8 ORF clone (NM_016700.3) Inquiry
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