shRNA set against Human MAP3K5 (NM_005923.3)

Name: shRNA set against Human MAP3K5 (NM_005923.3)
SKU: SHH337719
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH337719

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Product Information

Gene Information

Cat. No.	SHH337719
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	MAP3K5
Gene Name	MAP3K5 mitogen-activated protein kinase kinase kinase 5 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	MAP3K5 mitogen-activated protein kinase kinase kinase 5 [ Homo sapiens ]
Gene Symbol	MAP3K5
Synonyms	ASK1; MEKK5; MAPKKK5
Gene ID	4217
Uni Prot ID	Q99683
m RNA Refseq	NM_005923.3
Protein Refseq	NP_005914.1
Chromosome Location	6q22.33
Function	ATP binding; MAP kinase kinase kinase activity; cysteine-type endopeptidase activator activity involved in apoptotic process; magnesium ion binding; protein binding; protein homodimerization activity; protein kinase activity; protein kinase binding; protein phosphatase binding;
Pathway	Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; HIV-1 Nef: Negative effector of Fas and TNF-alpha, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem;
MIM	602448

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