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Panoply™ Human MAP3K5 Knockdown Stable Cell Line

Cat.No.
CSC-DC009175
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
MAP3K5
Synonyms
ASK1; MEKK5; MAPKKK5
Gene ID
UniProt ID
Q99683
mRNA Refseq
Protein Refseq
Chromosome Location
6q22.33
Function
ATP binding; MAP kinase kinase kinase activity; cysteine-type endopeptidase activator activity involved in apoptotic process; magnesium ion binding; protein binding; protein homodimerization activity; protein kinase activity; protein kinase binding; protein phosphatase binding;
Pathway
Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis Modulation and Signaling, organism-specific biosystem; Class I PI3K signaling events mediated by Akt, organism-specific biosystem; HIV-1 Nef: Negative effector of Fas and TNF-alpha, organism-specific biosystem; Insulin Signaling, organism-specific biosystem; Integrated Pancreatic Cancer Pathway, organism-specific biosystem;
MIM

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