shRNA set against Human LRRK2 (NM_198578.3)

Name: shRNA set against Human LRRK2 (NM_198578.3)
SKU: SHH335003
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH335003

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Product Information

Gene Information

Cat. No.	SHH335003
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	LRRK2
Gene Name	LRRK2 leucine-rich repeat kinase 2 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	LRRK2 leucine-rich repeat kinase 2 [ Homo sapiens ]
Gene Symbol	LRRK2
Synonyms	LRRK2; leucine-rich repeat kinase 2; PARK8, Parkinson disease (autosomal dominant) 8; leucine-rich repeat serine/threonine-protein kinase 2; DKFZp434H2111; FLJ45829; RIPK7; ROCO2; augmented in rheumatoid arthritis 17; PARK8; AURA17; DARDARIN;
GeneID	120892
Uni ProtID	Q5S007
mRNA Refseq	BC117180
Chromosome Location	12q12
Function	ATP binding; GTP binding; GTP-dependent protein kinase activity; GTP-dependent protein kinase activity; GTPase activator activity; NOT GTPase activity; MAP kinase kinase activity; nucleotide binding; protein binding; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity; tubulin binding;
Pathway	Parkinsons disease, organism-specific biosystem;
MIM	609007

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