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Panoply™ Human LRRK2 Knockdown Stable Cell Line

Cat.No.
CSC-DC008942
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
LRRK2
Synonyms
LRRK2; leucine-rich repeat kinase 2; PARK8, Parkinson disease (autosomal dominant) 8; leucine-rich repeat serine/threonine-protein kinase 2; DKFZp434H2111; FLJ45829; RIPK7; ROCO2; augmented in rheumatoid arthritis 17; PARK8; AURA17; DARDARIN;
Gene ID
UniProt ID
Q5S007
mRNA Refseq
BC117180
Chromosome Location
12q12
Function
ATP binding; GTP binding; GTP-dependent protein kinase activity; GTP-dependent protein kinase activity; GTPase activator activity; NOT GTPase activity; MAP kinase kinase activity; nucleotide binding; protein binding; protein homodimerization activity; protein kinase activity; protein serine/threonine kinase activity; tubulin binding;
Pathway
Parkinsons disease, organism-specific biosystem;
MIM

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