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shRNA set against Human KDM5C (NM_004187.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH324255

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Gene Information

Cat. No. SHH324255
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr KDM5C
Gene Name KDM5C lysine (K)-specific demethylase 5C [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name KDM5C lysine (K)-specific demethylase 5C [ Homo sapiens ]
Gene Symbol KDM5C
Synonyms MRXJ; SMCX; MRXSJ; XE169; MRXSCJ; JARID1C; DXS1272E
Gene ID 8242
Uni Prot ID P41229
m RNA Refseq NM_001146702.1
Protein Refseq NP_001140174.1
Chromosome Location Xp11.22-p11.21
Function DNA binding; histone demethylase activity (H3-K4 specific); molecular_function; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; zinc ion binding;
MIM 314690
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