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shRNA set against Human ERN1(NM_001433.3)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH039017

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Gene Information

Cat. No. SHH039017
Description Each set contains 4 shRNA expression constructs. The hairpin consists of a 7 base loop and 19~29 base stem optimized for the specific gene sequence. The sequences of 19~29mer shRNAi will be delivered with shRNA clones.
Gene Abbr ERN1
Gene Name ERN1 endoplasmic reticulum to nucleus signaling 1 [ Homo sapiens ]
Species Human
Report Gene eGFP
Promoter H1
Format 5 mu;g purified plasmid
Shipping Typically ships in 2-3 weeks
Gene Name ERN1 endoplasmic reticulum to nucleus signaling 1 [ Homo sapiens ]
Gene Symbol ERN1
Synonyms IRE1; IRE1P; IRE1a; hIRE1p
Gene Description endoplasmic reticulum to nucleus signalling 1
Gene ID 2081
Uni Prot ID O75460
m RNA Refseq NM_001433.3
Protein Refseq NP_001424.3
Chromosome Location 17q24.2
Function ATP binding; endoribonuclease activity; endoribonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; magnesium ion binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity;
Pathway Activation of Chaperones by IRE1alpha, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem;
MIM 604033
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