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Panoply™ Human ERN1 Knockdown Stable Cell Line

Cat.No.
CSC-DC005059
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
ERN1
Synonyms
IRE1; IRE1P; IRE1a; hIRE1p
Gene Description
endoplasmic reticulum to nucleus signalling 1
Gene ID
UniProt ID
O75460
mRNA Refseq
Protein Refseq
Chromosome Location
17q24.2
Function
ATP binding; endoribonuclease activity; endoribonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; magnesium ion binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity;
Pathway
Activation of Chaperones by IRE1alpha, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Protein processing in endoplasmic reticulum, organism-specific biosystem;
MIM

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