shRNA set against Human Apaf1 (NM_001160.2)

Name: shRNA set against Human Apaf1 (NM_001160.2)
SKU: SHH238006
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH238006

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Gene Information

Cat. No.	SHH238006
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	Apaf1
Gene Name	APAF1 apoptotic peptidase activating factor 1 [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	APAF1 apoptotic peptidase activating factor 1 [ Homo sapiens ]
Gene Symbol	APAF1
Synonyms	CED4; APAF-1
Gene Description	apoptotic peptidase activating factor 1
GeneID	317
Uni ProtID	O14727
mRNA Refseq	NM_013229.2
Protein Refseq	NP_037361.1
Chromosome Location	12q23
Function	ADP binding; ATP binding; cysteine-type endopeptidase activator activity involved in apoptotic process; nucleotide binding; protein binding;
Pathway	Activation of caspases through apoptosome-mediated cleavage, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Alzheimers Disease, organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; Apoptosis, organism-specific biosystem;
MIM	602233

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