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APAF1


Official Full Name
apoptotic peptidase activating factor 1
Organism
Homo sapiens
Gene ID
317
Background
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Synonyms
CED4; APAF-1

Cat.No. Product Name Price
SHG032743 shRNA set against Rat Apaf1(NM_023979.1) Inquiry
SHH238006 shRNA set against Human Apaf1 (NM_001160.2) Inquiry
SHG032633 shRNA set against Mouse Apaf1(NM_001042558.1) Inquiry
SHG032634 shRNA set against Human APAF1(NM_013229.2) Inquiry
SHG032645 shRNA set against Human APAF1(NM_181869.1) Inquiry
SHG032713 shRNA set against Human APAF1(NM_013229.2) Inquiry
SHG032737 shRNA set against Human APAF1(NM_181869.1) Inquiry
SHG032761 shRNA set against Human APAF1(NM_001160.2) Inquiry
SHG032779 shRNA set against Human APAF1(NM_181861.1) Inquiry
SHG032797 shRNA set against Human APAF1(NM_181868.1) Inquiry
SHG032815 shRNA set against Mouse Apaf1(NM_009684.2) Inquiry
SHH238010 shRNA set against Mouse Apaf1 (NM_009684.2) Inquiry
SHH238014 shRNA set against Rat Apaf1 (NM_023979.1) Inquiry
SHW015034 shRNA set against Danio rerio APAF1 (NM_131608) Inquiry
Cat.No. Product Name Price
CDFG011998 Human APAF1 cDNA Clone(NM_181869.1) Inquiry
MiUTR1H-00451 APAF1 miRNA 3'UTR clone Inquiry
MiUTR1H-00450 APAF1 miRNA 3'UTR clone Inquiry
MiUTR1H-00449 APAF1 miRNA 3'UTR clone Inquiry
MiUTR1H-00448 APAF1 miRNA 3'UTR clone Inquiry
MiUTR1H-00447 APAF1 miRNA 3'UTR clone Inquiry
CDFR012234 Rat Apaf1 cDNA Clone(NM_023979.1) Inquiry
CDFH000929 Human APAF1 cDNA Clone(NM_013229.2) Inquiry
CDFH000928 Human APAF1 cDNA Clone(NM_001160.2) Inquiry
CDFG012001 Human APAF1 cDNA Clone(NM_181868.1) Inquiry
MiUTR1M-01556 APAF1 miRNA 3'UTR clone Inquiry
MiUTR1M-01557 APAF1 miRNA 3'UTR clone Inquiry
CDFG011996 Human APAF1 cDNA Clone(NM_181861.1) Inquiry
CDCR379311 Rat Apaf1 ORF Clone(NM_023979.1) Inquiry
CDCR353786 Human APAF1 ORF Clone(NM_001160.2) Inquiry
CDCR028640 Mouse Apaf1 ORF clone (NM_001042558.1) Inquiry
CDCR028638 Human APAF1 ORF clone (NM_181869.1) Inquiry
CDCR028636 Human APAF1 ORF clone (NM_181868.1) Inquiry
CDCR028634 Human APAF1 ORF clone (NM_181861.1) Inquiry
CDCR028632 Human APAF1 ORF clone (NM_013229.2) Inquiry
CDCH015916 Mouse Apaf1 ORF clone(NM_009684.2) Inquiry
CDCB181727 Rabbit APAF1 ORF clone (XM_008257013.1) Inquiry
CDCB176509 Danio rerio APAF1 ORF Clone (NM_131608) Inquiry
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