shRNA set against Human ATR (NM_001184.3)

Name: shRNA set against Human ATR (NM_001184.3)
SKU: SHH243462
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : SHH243462

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Product Information

Gene Information

Cat. No.	SHH243462
Description	The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr	ATR
Gene Name	ATR ataxia telangiectasia and Rad3 related [ Homo sapiens ]
Species	Human
Report Gene	GFP
Storage	The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.

Gene Name	ATR ataxia telangiectasia and Rad3 related [ Homo sapiens ]
Gene Symbol	ATR
Synonyms	FRP1; MEC1; SCKL; FCTCS; SCKL1
Gene Description	ataxia telangiectasia and Rad3 related
Gene ID	545
Uni Prot ID	Q13535
m RNA Refseq	NM_001184.3
Protein Refseq	NP_001175.2
Chromosome Location	3q23
Function	ATP binding; DNA binding; MutLalpha complex binding; MutSalpha complex binding; protein binding; protein kinase activity; protein serine/threonine kinase activity;
Pathway	Activation of ATR in response to replication stress, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; Chromosome Maintenance, organism-specific biosystem;
MIM	601215

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