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shRNA set against Human ADAR (NM_001111.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH232030

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Gene Information

Cat. No. SHH232030
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr ADAR
Gene Name ADAR adenosine deaminase, RNA-specific [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name ADAR adenosine deaminase, RNA-specific [ Homo sapiens ]
Gene Symbol ADAR
Synonyms DSH; G1P1; IFI4; P136; ADAR1; DRADA; DSRAD; IFI-4; K88DSRBP
Gene ID 103
Uni Prot ID P55265
m RNA Refseq NM_001025107.2
Protein Refseq NP_001020278.1
Chromosome Location 1q21.3
Function DNA binding; double-stranded RNA adenosine deaminase activity; double-stranded RNA adenosine deaminase activity; double-stranded RNA binding; metal ion binding; protein binding;
Pathway C6 deamination of adenosine, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytosolic DNA-sensing pathway, organism-specific biosystem; Cytosolic DNA-sensing pathway, conserved biosystem; Formation of editosomes by ADAR proteins, organism-specific biosystem; Gene Expression, organism-specific biosystem; Immune System, organism-specific biosystem;
MIM 146920
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