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shRNA set against Human A2M (NM_000014.4)

For research use only. Not intended for any clinical use.

Cat. No. :   SHH228270

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Gene Information

Cat. No. SHH228270
Description The SureSilencing trade; shRNA Plasmids are designed to specifically knock down the expression of individual genes by RNA interference under either transient (with GFP) or stable transfection (for hygromycin, neomycin or puromycin-resistance) conditions after performance of the appropriate enrichment or selection procedures, respectively. Each vector contains the shRNA under control of the U1 promoter and either the GFP gene, for the enrichment of transiently transfected cells, or the neomycin or puromycin resistance genes, for the selection of stably transfected cells.
Gene Abbr A2M
Gene Name A2M alpha-2-macroglobulin [ Homo sapiens ]
Species Human
Report Gene GFP
Storage The SureSilencing shRNA Plasmids are shipped on dry ice or cold packs. Store all tubes at -20°C.
Gene Name A2M alpha-2-macroglobulin [ Homo sapiens ]
Gene Symbol A2M
Synonyms A2MD; CPAMD5; FWP007; S863-7
Gene Description alpha-2-macroglobulin
GeneID 2
Uni ProtID P01023
mRNA Refseq NM_000014.4
Protein Refseq NP_000005.2
Chromosome Location 12p13.31
Function enzyme binding; growth factor binding; interleukin-1 binding; interleukin-8 binding; protein binding; serine-type endopeptidase inhibitor activity; tumor necrosis factor binding;
Pathway Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; HDL-mediated lipid transport, organism-specific biosystem; Hemostasis, organism-specific biosystem; IL6-mediated signaling events, organism-specific biosystem;
MIM 103950
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