Recombinant Mouse Tnfrsf13C (C-Fc)

Name: Recombinant Mouse Tnfrsf13C (C-Fc)
SKU: RP00608
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00608 Tag : C-Fc

Expressed Region : Ser10-Ala 71 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00608
Description	Recombinant Mouse Tnfrsf13C (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Ser10-Ala 71 with a Fc tag at the C terminus.
Species	Mouse
Tag	C-Fc
Mol Weight	33.8 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Ser10-Ala 71
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Tnfrsf13C
Synonyms	BAFF R; BAFFR; BR3; CD268; TNFRSF13C

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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

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