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Recombinant Mouse IL-5RA (C-6His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00372 Tag :   C-6His

Expressed Region :   Asp18-His339 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00372
Description The Recombinant Mouse IL-5RA (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Asp18-His339 with a 6His tag at the C terminus.
Species Mouse
Tag C-6His
Mol Weight 37.6 KDa
Conjugate Unconjugated
Format Powder
Expressed Region Asp18-His339
Expression System Human Cell
Formulation Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Gene Il5ra
Synonyms Interleukin-5 receptor subunit alpha; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; CD125; Il5ra; Il5r
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The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.

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