Recombinant Mouse GHR (C-Fc)

Name: Recombinant Mouse GHR (C-Fc)
SKU: RP00289
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00289 Tag : C-Fc

Expressed Region : Met1-Gln273 Expression System : Human Cell

Inquire for Price

Product Information

Gene Information

Cat. No.	RP00289
Description	The Recombinant Mouse GHR (C-Fc) is produced in our Human Cell expression system. The amino acid region expressed is Met1-Gln273 with a Fc tag at the C terminus.
Species	Mouse
Tag	C-Fc
Mol Weight	58.3 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met1-Gln273
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Ghr
Synonyms	growth hormone binding protein; growth hormone receptor; serum binding protein; Somatotropin receptor;GHR; GH receptor; GHBP

Quick Inquiry

Background

Q & A

Customer Reviews

This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *