Recombinant Mouse DDR1 (C-6His)

Name: Recombinant Mouse DDR1 (C-6His)
SKU: RP00050

Cat.No. : RP00050 Tag: C-6His

Expressed Region: Asp22-Thr414 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00050
Description	The Recombinant Mouse DDR1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Asp22-Thr414 with a 6His tag at the C terminus.
Species	Mouse
Tag	C-6His
Mol. Weight	45 KDa
Expressed Region	Asp22-Thr414
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Ddr1
Background	Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms	Epithelial discoidin domain-containing receptor 1; Epithelial discoidin domain receptor 1; CD167 antigen-like family member A; Cell adhesion kinase; Discoidin receptor tyrosine kinase; HGK2; CD167a; DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE

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