Recombinant Human TMEM173 (N-Sumo-6His)

Name: Recombinant Human TMEM173 (N-Sumo-6His)
SKU: RP00539
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00539 Tag : N-Sumo-6His

Expressed Region : Val155-Val341 Expression System : E.coli

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Product Information

Gene Information

Cat. No.	RP00539
Description	Recombinant Human TMEM173 (N-Sumo-6His) is produced in our E.coli expression system. The amino acid region expressed is Val155-Val341 with a Sumo-6His tag at the N terminus.
Species	Human
Tag	N-Sumo-6His
Mol Weight	33.8 KDa
Conjugate	Unconjugated
Format	Liquid
Expressed Region	Val155-Val341
Expression System	E.coli
Formulation	Supplied as a 0.2 μm filtered solution of 20mM HEPES, 100mM NaCl, 10% Glycerol, pH8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.

Target Gene	TMEM173
Background	This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
Synonyms	Stimulator of interferon genes protein;TMEM173;Mediator of IRF3 activation;sting;

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