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Mouse Tmem173 cDNA Clone(NM_028261.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL013925

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Product Information

Gene Information

Cat. No. CDFL013925
Product Type cDNA clone
Gene Abbr Tmem173
Species Mouse
Size 10 ug
Target Gene TMEM173
Background This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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