Recombinant Human RRM2 (C-6His)

Name: Recombinant Human RRM2 (C-6His)
SKU: RP00214
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00214 Tag : C-6His

Expressed Region : Met1-Phe389 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00214
Description	The Recombinant Human RRM2 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Met1-Phe389 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	45.9 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Met1-Phe389
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 5% Trehalose, pH 8.0.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	RRM2
Background	This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
Synonyms	Ribonucleoside-Diphosphate Reductase Subunit M2; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; RRM2; RR2

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