Recombinant Human PDGFRB (C-6His)

Name: Recombinant Human PDGFRB (C-6His)
SKU: RP00236
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00236 Tag : C-6His

Expressed Region : Leu33-Phe530 Expression System : Human Cell

Inquire for Price

Product Information

Gene Information

Cat. No.	RP00236
Description	The Recombinant Human PDGFRB (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Leu33-Phe530 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	57.17 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Leu33-Phe530
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	PDGFRB
Synonyms	Platelet-Derived Growth Factor Receptor Beta; PDGF-R-Beta; PDGFR-Beta; Beta Platelet-Derived Growth Factor Receptor; Beta-Type Platelet-Derived Growth Factor Receptor; CD140 Antigen-Like Family Member B; Platelet-Derived Growth Factor Receptor 1; PDGFR-1; CD140b; PDGFRB; PDGFR; PDGFR1

Quick Inquiry

Background

Q & A

Customer Reviews

The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia.

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *