Recombinant Human OSM (N-Avi-His)

Name: Recombinant Human OSM (N-Avi-His)
SKU: RP00664
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00664 Tag : N-Avi-His

Expressed Region : Ala26-Arg221 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00664
Description	The Recombinant Human OSM (N-Avi-His) is produced in our Human Cell expression system. The amino acid region expressed is Ala26-Arg221 with a Avi-His tag at the N terminus.
Species	Human
Tag	N-Avi-His
Mol Weight	30-35 kDa, on SDS-PAGE under reducing conditions.
Conjugate	Biotinylated
Format	Powder
Expressed Region	Ala26-Arg221
Expression System	Human Cell
Formulation	Lyophilized after extensive dialysis against PBS.
Purity	> 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Endotoxin Level	< 0.2 EU/μg of protein by gel clotting method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	OSM
Synonyms	OncoM; oncostatin M

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This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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