Recombinant Human MMP-1 (C-6His)

Name: Recombinant Human MMP-1 (C-6His)
SKU: RP00009

Cat.No. : RP00009 Tag: C-6His

Expressed Region: Phe20-Asn469 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00009
Description	The Recombinant Human MMP-1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Phe20-Asn469 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	52.88 KDa
Expressed Region	Phe20-Asn469
Expression System	Human Cell
Format	Liquid
Formulation	Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 2mM CaCl₂, 1mM DTT, 0.05%Brij35, 10% Glycerol, pH 5.0.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.

Target Gene	MMP-1
Background	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Synonyms	Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG

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