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Recombinant Human MMP-1 (C-6His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00009 Tag :   C-6His

Expressed Region :   Phe20-Asn469 Expression System :   Human Cell

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Product Information

Gene Information

Cat. No. RP00009
Description The Recombinant Human MMP-1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Phe20-Asn469 with a 6His tag at the C terminus.
Species Human
Tag C-6His
Mol Weight 52.88 KDa
Conjugate Unconjugated
Format Liquid
Expressed Region Phe20-Asn469
Expression System Human Cell
Formulation Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 2mM CaCl2, 1mM DTT, 0.05%Brij35, 10% Glycerol, pH 5.0.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Target Gene MMP-1
Synonyms Interstitial Collagenase; Fibroblast Collagenase; Matrix Metalloproteinase-1; MMP-1; MMP1; CLG
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This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

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